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SYSTEM AND METHOD FOR ASSESSING THE RISK OF COLORECTAL CANCER

机译:评估结直肠癌风险的系统和方法

摘要

Colorectal cancer is a severe disease, if not assessed properly, it may lead to the death of an individual. A system and method for assessing the risk of colorectal cancer has been provided. The system is configured to assess individuals to check the risk of presence of colorectal cancer (CRC) and/or adenomatous (colonic/ rectal) polyps, by quantifying the abundance of sensory proteins in their gut microbiome. The system further categorizes the person into one of healthy, adenoma and cancerous categories based on the nature and abundance of sensory proteins in the gut microbiome. The system further describes microbiota based therapeutics for treatment of the person with colorectal adenoma and/or cancer through administration of at least one of a consortium of healthy microbes, antibiotic drugs and pre-/ pro-/ syn-/ post-biotic compounds or fecal microbiome transplant which could modulate the disease microbiome composition towards a healthy equilibrium.
机译:结直肠癌是一种严重的疾病,如果没有适当评估,它可能导致个人的死亡。提供了用于评估结直肠癌风险的系统和方法。该系统被配置为通过量化其肠道微生物组中的感觉蛋白质,评估个体以检查结肠直肠癌(CRC)和/或腺嘌呤)息肉的存在风险。该系统根据肠道微生物组中的感觉蛋白质的性质和丰度,将该人分为健康,腺瘤和癌症类别中的一种。该系统进一步描述了基于微生物群的治疗方法,用于治疗具有结直肠腺瘤和/或癌症的人,通过施用至少一个健康的微生物,抗生素药物和/促型/单次/术后生物化合物或粪便微生物组移植,其可以调节疾病微生物组合物朝向健康平衡。

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