首页> 外国专利> COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING INFECTIOUS DISEASE CAUSED BY TUBERCULOSIS AND NON-TUBERCULOUS MYCOBACTERIAL INFECTION

COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING INFECTIOUS DISEASE CAUSED BY TUBERCULOSIS AND NON-TUBERCULOUS MYCOBACTERIAL INFECTION

机译:用于预防,减轻或治疗由结核病和非结核性分枝杆菌感染引起的传染病的组合物

摘要

The present invention relates to a pharmaceutical composition for preventing, alleviating, or treating infectious disease caused by tuberculosis and non-tuberculous mycobacterial infection. The composition according to the present invention has a remarkable synergistic effect on Mycobacterium tuberculosis and nontuberculous mycobacteria and, particularly, on the inhibition of proliferation and growth of the strains of which the growth rate is further increased when the expression level of IFN-β, which is expressed in host cells of macrophages, is increased. Because of the effects, infectious disease caused by Mycobacterium tuberculosis and nontuberculous mycobacteria, of which the main host cells are macrophages, can be very effectively treated.
机译:本发明涉及用于预防,缓解或治疗由结核病和非结核性分枝杆菌感染引起的传染病的药物组合物。根据本发明的组合物对结核分枝杆菌和不泛骨分枝杆菌具有显着的协同作用,特别是在IFN-β的表达水平进一步增加生长速率的菌株的增殖和生长的抑制作用在巨噬细胞的宿主细胞中表达,增加。由于效果,由结核分枝杆菌和非萎缩分枝杆菌引起的传染病,其中主要宿主细胞是巨噬细胞,可以非常有效地治疗。

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