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REGENERATING FUNCTIONAL NEURONS FOR TREATMENT OF SPINAL CORD INJURY AND ALS
REGENERATING FUNCTIONAL NEURONS FOR TREATMENT OF SPINAL CORD INJURY AND ALS
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机译:再生功能神经元治疗脊髓损伤和ALS
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摘要
This document provides methods and materials involved in treating mammals having a spinal cord injury (SCI). For example, methods and materials for administering a composition containing exogenous nucleic acid encoding a NeuroD1polypeptide (or a biologically active fragment thereof) alone or in combination with a Dlx2 polypeptide (or a biologically active fragment thereof) to a mammal having SCI are provided. This document also provides methods and materials involved in treating mammals having amyotrophic lateral sclerosis (ALS). For example, methods and materials for administering a composition containing exogenous nucleic acid encoding a NeuroD1 polypeptide (or a biologically active fragment thereof) alone or in combination with an Isl1 polypeptide (or a biologically active fragment thereof) to a mammal having ALS are provided.
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