METHODS AND COMPOSITIONS FOR PRODUCING STEM CELL DERIVED SPINAL GABA INHIBITORY NEURONS FOR USE IN TREATMENT OF SPINAL CORD INJURY

摘要

Disclosed herein are in vitro methods of inducing differentiation of human stem cells into spinal GABA interneurons, and spinal dorsal interneurons domain 4 (dl4) progenitors thereof, and cells generated by such methods. The presently disclosed subject matter also provides for uses of such cells for treating spinal cord injury.