Method of predicting therapeutic effect of joint rheumatoid arthritis by biological formulation

摘要

An objectof thepresentinventionprior to administering thebiologicto therheumatoidarthritispatient,simple,inexpensive,and accurately,the therapeutic effect(in particular,whethermadeincomplete remissionstate),or symptoms ofimprovementTo provide a method of determining.Solutions SGP130,IP-10,STNFRI,STNFRII,GM-CSF,IL-1β,IL-2,IL-5,IL-6,IL-7,IL-8,IL-9,IL-10,IL-12,IL-13,IL-15,EOTAXIN,VEGF,MCP-1,TNF-α,IFN-γ,FGFBASIC,PDGF-BB,SIL-6R,And by utilizing one or more serum concentrations selected from the group consisting of MIP-1α,Before administering a biological formulation targeted with inflammatory cytokines,Therapeutic effect on rheumatoid arthritis patients (the degree of improvement of symptoms and possibility of remission),Simple and inexpensive,It is possible for any facility,Moreover, it can be predicted with high accuracy.[Select figure] None