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Methods for treating ocular inflammatory diseases

机译:治疗眼炎疾病的方法

摘要

A method of treating non-infectious, inflammatory blepharitis includes administering to the affected eye of a subject an effective amount of an active ingredient in an ophthalmically acceptable vehicle for a sufficient period of time to treat the non-infectious, inflammatory blepharitis. The active ingredient consists essentially of a glucocorticoid in an ophthalmically acceptable vehicle that includes an aqueous polymer suspension that when mixed with tear fluid provides a sustained release of said active ingredient. The aqueous polymer suspension includes a carboxyl-containing polymer having less than about 5% by weight cross-linking agent and has a viscosity in a range from about 1,000 to about 30,000 centipoises. A kit includes: (a) a composition comprising about 0.1% by weight dexamethasone in this ophthalmically acceptable vehicle and (b) instructions for using the composition of (a) for the treatment of blepharitis.
机译:一种治疗非感染性的炎性障碍性障碍炎的方法包括给受试者的受影响的眼睛施用有效量的眼科上可接受的载体中的活性成分,以便足够的时间来治疗非传染性的炎症性睑炎。活性成分基本上由眼科上可接受的载体中的糖皮质激素组成,其包括含水聚合物悬浮液,当与泪液混合时提供所述活性成分的持续释放。含水聚合物悬浮液包括含羧基的聚合物,其重量的交联剂小于约5%,粘度为约1,000至约30,000厘泊。试剂盒包括:(a)在该眼科上可接受的载体中包含约0.1重量%的地塞米松的组合物,并使用(b)使用(a)的组成来治疗睑炎。

著录项

  • 公开/公告号US10980818B2

    专利类型

  • 公开/公告日2021-04-20

    原文格式PDF

  • 申请/专利权人 SUN PHARMA GLOBAL FZE;

    申请/专利号US201816237110

  • 发明设计人 LYLE M BOWMAN;KAMRAN HOSSEINI;

    申请日2018-12-31

  • 分类号A61K31/573;A61K47/34;A61P27/02;A61K9;

  • 国家 US

  • 入库时间 2022-08-24 18:17:42

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