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Nicotinic acid or isonicotinic acid compound and use thereof
Nicotinic acid or isonicotinic acid compound and use thereof
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机译:烟酸或异烟酸化合物及其用途
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摘要
Disclosed are a nicotinic acid or isonicotinic acid compound and a use thereof. The compound is the compound shown in Formula I, or a pharmaceutically acceptable salt, ester or solvate thereof. Efficacy tests demonstrate that the nicotinic acid compound can inhibit botulinum toxin endopeptidase activity in vitro, and has a significant protective effect on mice poisoned with botulinum toxin. On this basis, the compound may be used to prepare a drug preventing and/or treating botulinum toxin exposure and/or poisoning.; 展开▼