首页> 外文会议>12th Romanian International Conference on Chemistry and Chemical Engineering Sep 13-15, 2001 Bucharest, Romania >Purposeful search physiologically active compounds (PAC) with participation of nicotinic acid (NA) and some alkaline and alkaline earth metals
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Purposeful search physiologically active compounds (PAC) with participation of nicotinic acid (NA) and some alkaline and alkaline earth metals

机译:有针对性地搜索具有烟酸(NA)和一些碱金属和碱土金属的生理活性化合物(PAC)

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摘要

By interaction of NA with carbonates of a lithium and potassium and with magnesia and calcium the conforming salts of NA are obtained. The pharmacological researches of these salts have shown that NA of lithium has the expressed psychotropic effect of tranquilizalional character. The magnesium and the potassium salts of NA in an admixture have cardiotropic action, including antiarrhytmical. The calcium salt in experiment has appreciable antiarrhytmical action in the attitude of an anaphylaxis and contact dermatitis.
机译:通过NA与锂和钾的碳酸盐以及与氧化镁和钙的相互作用,得到NA的保形盐。这些盐的药理研究表明,锂的NA具有镇定特性的明显精神作用。混合物中NA的镁盐和钾盐具有抗心律作用,包括抗心律失常药。实验中的钙盐在过敏反应和接触性皮炎方面具有明显的抗心律失常作用。

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