The present invention relates to an alginic acid oligosaccharide diacid composition comprising mannuronic acid diacid of formula (IV) or a pharmaceutically acceptable salt thereof, wherein n is an integer selected from 1 to 9, and m is selected from 0, 1 or 2. And m'is selected from 0 or 1, and the total weight of the alginic acid oligosaccharide diacid having n=1 to 5 accounts for at least 60% of the total weight of the composition; The total weight of glutonic acid accounts for up to 50% of the total weight of the composition. Equation (IV)
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