Medicines that are used to treat diseases are conventionally made from starting materials that are derived from fossil fuels and therefore contain essentially no 14C. In the present invention, medicines can be partially or fully derived from biological sources and therefore contain about one part per trillion (ppt) 14C. These compounds have been discovered as superior for the treatment of disease because they have surprisingly been found to substantially increase patient compliance. Compounds and methods of using partially or fully bio-based pharmaceutically active compounds to track metabolites are also disclosed.
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