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PENICILLIN-BINDING PROTEIN INHIBITORS

机译:青霉素结合蛋白抑制剂

摘要

Described herein are certain boron-containing compounds, compositions, preparations and their use as modulators of the transpeptidase function of bacterial penicillin-binding proteins and as antibacterial agents. In some embodiments, the compounds described herein inhibit penicillin-binding proteins. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
机译:本文描述的是含硼的化合物,组合物,制剂及其用作细菌青霉素结合蛋白和抗菌剂的转酯酶功能的调节剂。在一些实施方案中,本文所述的化合物抑制青霉素结合蛋白。在某些实施方案中,本文所述的化合物可用于治疗细菌感染。

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