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METHOD FOR CLASSIFYING MONITORING RESULTS FROM AN ANALYTICAL SENSOR SYSTEM ARRANGED TO MONITOR MOLECULAR INTERACTIONS

机译:用于对布置成监测分子相互作用的分析传感器系统进行分类结果的方法

摘要

Disclosed is a method for classifying monitoring results from an analytical sensor system (20) arranged to monitor molecular interactions at a sensing surface, wherein detection curves representing progress of the molecular interactions with time are produced. The method comprises steps of: acquiring (100) a set of detection curves, fitting (101) a first mathematical model to the set of detection curves; calculating (102) a set of features from the set of detection curves and fitted mathematical model; based on the calculated set of features, classifying (103) each detection curve into quality classification group; and based on the classification determining which detection curves to use in kinetic analysis of the monitored molecular interactions.
机译:公开了一种用于对被布置成监测感测表面处的分子相互作用的分析传感器系统(20)进行分类的方法,其中产生表示与时间的分子相互作用进展的检测曲线。该方法包括步骤:获取(100)一组检测曲线,拟合(101)对该组检测曲线的第一数学模型;计算(102)一组检测曲线集和拟合数学模型的特征;基于计算的特征集,将每个检测曲线分类(103)分类为质量分类组;基于分类确定监测分子相互作用的动力学分析中使用的检测曲线。

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