COMPOSITIONS THAT PREFERENTIALLY POTENTIATE SUBTYPES OF GABAA RECEPTORS AND METHODS OF USE THEREOF

摘要

The invention provides compositions containing isomerically pure forms of neurosteroids that permit preferential modulation of different subtypes of GABA_A receptors, such as preferential modulation of α4β3δ GABA_A receptors over α1β2γ2 GABA_A receptors. The invention also provides methods of treating GABA_A disorders using such compositions.