Screening method for skin barrier function enhancing drug and skin barrier function evaluation method using the amount of epidermal serine racemase and / or D-serine as an index

摘要

PROBLEM TO BE SOLVED: To develop a method for screening drugs having the effect of increasing skin barrier function in in vitro studies and to evaluate barrier function in the skin.SOLUTION: Candidate drugs can be screened by using the activity and/or expression level of serine racemase as an indicator.