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Protein homeostasis regulator enriched cell derived vesicle and method for manufacturing the same

机译:蛋白质稳态调节剂富集细胞衍生的囊泡和制造方法

摘要

The present invention relates to a cell-derived vesicle rich in intracellular homeostasis modulators and a method for producing the same, wherein the cell-derived vesicle of the present invention contains a specific protein more abundantly compared to the naturally secreted exosomes or derived cells. It is characterized, and due to these characteristics, it can be used for various purposes, such as pharmaceutical compositions, diagnostic compositions, and drug delivery compositions. Using a cell-derived vesicle rich in intracellular protein homeostasis regulating factors of the present invention and a method for producing the same, the intracellular protein homeostasis regulating factor can be easily delivered to, for example, a target such as a cell, thereby facilitating intracellular protein homeostasis. I can keep it. Therefore, it can be used as “for preventing or treating diseases caused by failure to regulate intracellular protein homeostasis” or “for preventing aging”, and thus can be widely used in the pharmaceutical industry.
机译:本发明涉及富含细胞内稳态调节剂的细胞衍生的囊泡及其制造方法,其中本发明的细胞衍生的囊泡含有与天然分泌的外索物或衍生细胞相比的特定蛋白质。其特征在于,由于这些特性,它可以用于各种目的,例如药物组合物,诊断组合物和药物递送组合物。使用富含细胞衍生的囊泡富含细胞内蛋白质稳态调节因子的发明内容和制造方法,可以容易地递送细胞内蛋白稳态调节因子,例如诸如细胞的靶,从而促进细胞内蛋白质稳态。我可以保留它。因此,它可以用作“用于预防或治疗因未能调节细胞内蛋白质稳态造成的疾病”或“用于预防老化”,因此可以广泛用于制药行业。

著录项

  • 公开/公告号KR102236375B1

    专利类型

  • 公开/公告日2021-04-05

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR1020200061867

  • 申请日2020-05-22

  • 分类号C12N5/078;A61K35/17;A61K35/26;A61K35/28;A61K47/46;A61P25/16;A61P25/18;C12N5/0775;C12N5/0783;

  • 国家 KR

  • 入库时间 2022-08-24 18:07:05

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