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SYSTEMS AND METHODS FOR DELIVERY OF PERITONEAL DIALYSIS (PD) SOLUTIONS WITH INTEGRATED INTER-CHAMBER DIFFUSER

机译:具有集成室间扩散器腹膜透析(PD)溶液的腹膜透析(PD)溶液的系统和方法

摘要

The invention provides, in some aspects, a container system for medical solutions such as peritoneal dialysis (PD) solutions. The invention particularly features a system which includes a first compartment that contains a first medical solution, e.g., a PD osmotic agent, and a second compartment that contains a second medical solution, e.g., a PD buffer agent. The compartments maintain their respective contents separately from one another for purposes of transport, storage and/or sterilization. However, the compartments are fluidly couplable, so that their respective contents can be combined with one another, e.g., following sterilization of the agents and prior to their introduction into the patient's abdomen. To that end, a container system can include a diffuser that is disposed in a fluid pathway between the first and second compartments, e.g., to facilitate homogeneous mixing of the first and second PD agents. That diffuser is disposed within and moves relative to a structure, such as a port that defines the fluid pathway between those compartment. Thus, for example, the diffuser can comprise a body that “floats” within that pathway-defining structure and that moves from one end to the other (and/or to from points there between), depending on a direction of solution flow through the structure.
机译:在一些方面,本发明提供了一种用于医疗解决方案的容器系统,例如腹膜透析(PD)溶液。本发明特别是一种系统,该系统包括第一隔室,其包含第一医疗溶液,例如Pd渗透剂和第二隔室,其含有第二医疗溶液,例如Pd缓冲剂。盒子以彼此分开地保持各自的内容,以便运输,储存和/或灭菌。然而,隔室是流体可耦合的,因此它们各自的内容物可以彼此组合,例如,在药剂的灭菌之后,并且在它们进入患者的腹部之前。为此,容器系统可包括漫射器,该扩散器设置在第一和第二隔室之间的流体通路中,例如,以促进第一和第二PD剂的均匀混合。扩散器设置在内部并相对于结构移动,例如限定这些隔室之间的流体通路的端口。因此,例如,漫射器可包括在该途径限定结构内“浮动”的主体,并且从一端移动到另一端(和/或从之间的点之间移动),这取决于溶液流过的方向结构体。

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