Supercontinuum microscope for resonance and non-resonance enhanced linear and nonlinear images and time resolved microscope for tissues and materials

摘要

Supercontinuum (SC) (˜400 nm to ˜2500 nm) and a microscope produce enhanced microscopic images on sub-micron to cm scale of linear (χ₁) and nonlinear (χ₂, χ₃, χ₄ . . . ) processes via resonance including linear absorption, SHG, THG, SRG, SRL, SRS, 2PEF, 3PEF, 4PEF, and inverse Raman in a microscope for 2D and 3D imaging. Images and processes in 2D and 3D arise from electronic and vibrational resonances transitions in biological and medical tissues, cells, condensed matter applications. Resonant Stimulated Raman Scattering (RSRS) is proposed to improve vibrational imaging of biomaterials by using part of SC. Quantum mechanical processes from SC for 2 and 4 photons to improve resolution and imaging using entangled photons are described. The addition of time measuring instrument like a Streak camera and the scattering coefficient μ_s′ can be mapped to create images of tissue and biomaterial in 5D: Space (3D), Time, and Wavelength.