首页> 外国专利> Composition for preventing, treating, or improving skin disease induced by air pollutants comprising resorcinol or phenylethyl resorcinol

Composition for preventing, treating, or improving skin disease induced by air pollutants comprising resorcinol or phenylethyl resorcinol

机译:用于预防,治疗或改善通过污染物诱导的皮肤病的组合物,所述空气污染物包含间苯二酚或苯乙基间苯二酚

摘要

The present invention relates to a composition for preventing, treating, or improving skin diseases caused by air pollutants including resorcinol or phenylethylresorcinol, wherein resorcinol or phenylethylresorcinol according to the present invention is XRE (Xenobiotic Response Element) expression induced by air pollutants such as benzo (α) pyrene and fine dust, CYP1A1 (Cytochrome P450, family 1, subfamily A, polypeptide 1) protein or mRNA expression, or AhR (Aryl hydrocarbon) receptor) into the nucleus, it was confirmed that it suppressed skin irritation. Accordingly, it is expected that the resorcinol or phenylethyl resorcinol of the present invention can be usefully used in the field of developing therapeutics or improving agents for various skin diseases that may be caused by air pollutants.
机译:本发明涉及用于预防,治疗或改善由包含间苯二酚或苯基乙基乙烯醇的空气污染物引起的皮肤疾病的组合物,其中根据本发明的间苯二酚或苯基乙基乙烯醇是由空气污染物如苯佐( α)芘和细粉尘,CYP1A1(细胞色素P450,家庭1,亚家族A,多肽1)蛋白质或mRNA表达,或者AHR(芳基烃)受体)进入细胞核,证实它抑制了皮肤刺激。因此,预期本发明的间苯二酚或苯基乙基间苯甲醇可以用在发育治疗剂或改善剂的领域中,用于各种可能由空气污染物引起的皮肤疾病。

著录项

  • 公开/公告号KR20210033627A

    专利类型

  • 公开/公告日2021-03-29

    原文格式PDF

  • 申请/专利权人 성균관대학교산학협력단;

    申请/专利号KR1020190115134

  • 发明设计人 이종성;이승은;

    申请日2019-09-19

  • 分类号A61K31/05;A61K8/34;A61P17;A61Q17;A61Q19;

  • 国家 KR

  • 入库时间 2022-08-24 17:57:44

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