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PROLONGED FUNCTION OF LIVER ORGANOIDS AS AN IN VITRO MODEL FOR THE STUDY OF LIVER DISEASE
PROLONGED FUNCTION OF LIVER ORGANOIDS AS AN IN VITRO MODEL FOR THE STUDY OF LIVER DISEASE
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机译:肝脏有机体的长期功能作为肝病研究的体外模型
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摘要
Disclosed is a spheroid liver organoid comprising hepatic lineage cells such as human hepatocytes, hepatic stellate cells, and liver sinusoidal endothelial cells. Also provided are methods of using spheroid liver organoids for applications related to drug screening and toxicity screening. In particular, spheroid liver organoids are useful for high-throughput screens to identify compounds having efficacy for treating liver disease.
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