SYSTEM AND METHOD FOR PERSONALIZED KIDNEY EVALUATION, DIAGNOSIS AND THERAPY RECOMMENDATION

摘要

A system for evaluating a kidney includes a processing device including an input module configured to acquire patient information, the patient information including at least one of demographic data, diagnostic data, physiological data and intervention data. The processing device also includes an evaluation module, which is configured to input patient class data to an initial kidney model, the initial kidney model configured to simulate a physiological response of a kidney and configured to simulate fluid and solute transport through one or more spatial locations of the kidney. The evaluation module is also configured to input patient data corresponding to an individual patient and calculating a model response, and adjust at least one parameter of the initial kidney model based on a comparison of the patient data and the model response to personalize the initial kidney model for the individual patient.