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New biomarkers and methods for diagnosing and assessing traumatic brain injury

机译:诊断和评估创伤性脑损伤的新生物标志物和方法

摘要

The present disclosure relates to methods for diagnosing and assessing subjects who have or may have suffered head injury, such as traumatic brain injury (TBI). In particular, the present disclosure may use their detection and / or differential expression to assess the presence or absence of TBI in a subject, subjecting the subject to a particular type of TBI (eg, severe). Identify a variety of biomarkers that can be used as a basis for diagnosis as having a TBI or a subclass of mild TBI). A variety of TBI biomarkers may be detected individually or in combination and are important diagnostic tools, prognostic tools and / or TBI risk stratification as part of assessing a subject's TBI status. Can be used as a tool.
机译:本公开涉及用于诊断和评估具有或可能患有头部损伤的受试者的方法,例如创伤性脑损伤(TBI)。特别地,本公开可以使用它们的检测和/或差异表达,以评估受试者的对象中TBI的存在或不存在,使受试者经受特定类型的TBI(例如,严重)。鉴别各种生物标志物,可用作具有TBI或轻度TBI的TBI或亚类的诊断的基础。可以单独或组合检测多种TBI生物标志物,并且是重要的诊断工具,预后工具和/或TBI风险分层,作为评估受试者的TBI状态的一部分。可以用作工具。

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