首页> 外国专利> MICROFLUIDIC SEQUENCING DEVICE FOR MULTIPLYING AND SEPARATING MOLECULAR CHAINS, AND METHOD FOR SEPARATING MOLECULAR CHAINS OBTAINED FROM AN AMPLIFICATION REACTION

MICROFLUIDIC SEQUENCING DEVICE FOR MULTIPLYING AND SEPARATING MOLECULAR CHAINS, AND METHOD FOR SEPARATING MOLECULAR CHAINS OBTAINED FROM AN AMPLIFICATION REACTION

机译:用于倍增和分离分子链的微流体测序装置,以及从扩增反应中获得的分子链的方法

摘要

The invention relates to a microfluidic sequencing device (100) for multiplying and separating molecular chains. The sequencing device (100) is designed to receive biochemical material, and the sequencing device (100) has at least one supply opening (105) for supplying biochemical material into the sequencing device (100). The sequencing device (100) additionally has at least one microfluidic separation unit (101), said separation unit (101) having at least one separation channel (102) with at least one amplification cavity (115) for multiplying molecular chains supplied via the supply opening (105) as the biochemical material and with at least one separating unit (120) which is connected or can be connected to the amplification cavity (115) microfluidically and comprises a multi-porous material, wherein the separating unit (120) is designed to separate nucleic acids from other macromolecular components and/or to separate nucleic acids. Furthermore, the sequencing device (100) has at least one discharge opening (125a) for discharging nucleic acids separated in the separation unit (101) as biochemical material out of the sequencing device (100).
机译:本发明涉及微流体测序装置(100),用于乘以分离分子链。测序装置(100)设计成接收生物化学材料,并且测序装置(100)具有至少一个用于将生物化学材料供应到测序装置(100)中的供应开口(105)。测序装置(100)另外还具有至少一个微流体分离单元(101),所述分离单元(101)具有至少一个分离通道(102),其具有至少一个扩增腔(115),用于将通过供应供应的分子链乘以倍增作为生物化学材料和至少一个分离单元(120)的开口(105)连接或者可以连接到放大腔(115)微流出物并包括多孔材料,其中设计了分离单元(120)将来自其他大分子组分和/或分离的核酸分离核酸。此外,测序装置(100)具有至少一个排出开口(125a),用于排出在分离单元(101)中分离的核酸作为测序装置(100)中的生物化学材料。

著录项

  • 公开/公告号EP3790661A1

    专利类型

  • 公开/公告日2021-03-17

    原文格式PDF

  • 申请/专利权人 ROBERT BOSCH GMBH;

    申请/专利号EP20190724363

  • 发明设计人 HOFFMANN JOCHEN;

    申请日2019-05-02

  • 分类号B01L3;C12Q1/6874;

  • 国家 EP

  • 入库时间 2022-08-24 17:45:20

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