4β-amidotriazole linked podophyllotoxin derivatives as potential anticancer agents

摘要

The present invention relates to a compound of general formula (A). The invention provides asynthesis of new 4β-amidotriazole linked podophyllotoxin derivatives of general formulae 8a-z to 9a-z useful as potential anticancer agents against human cancer cell lines and process for the preparation thereof. Wherein n=0, 1 and R₁-R₅═[H, CI, F, CH₃, OCH₃, 3,4(-OCH₂O—), CF₃, OCF₃, m-OC₆H₅, OH];