P110-DELTA INHIBITORS TREAT AND PREVENT AUTOIMMUNITY WHILE SPARING THE ABILITY TO MOUNT AN IMMUNE RESPONSE TO EXOGENOUS IMMUNOGENS

摘要

Methods of using a phosphoinositide 3-kinase p110-delta inhibitor to treat, delay the onset, or slow the progression of an autoimmune disease or disorder in a subject, without suppressing the subject's B cell responses to exogenous antigens or rendering the subject immunocompromised, as well as pharmaceutical compositions containing phosphoinositide 3-kinase p110-delta inhibitors in amounts suitable for convenient and accurate administration within these therapeutic methods.