METHOD OF COUMARIN APPLICATION FOR INHIBITION OF DIFFERENT 'QUORUM SENSING' LUX/LUXR TYPE SYSTEMS IN BACTERIA

摘要

FIELD: pharmaceuticals.;SUBSTANCE: invention relates to pharmaceuticals, namely to the application of a plant-based coumarin compound for inhibition of a "quorum sensing" LuxI/LuxR type system in bacteria. The application of 7,8-dihydroxi-4-methylcoumarin as an inhibitor of a "quorum sensing" LuxI/LuxR type system in bacteria ; ;where A is a coumarin compound.;EFFECT: said compound is effective as an inhibitor of various "quorum sensing" LuxI/LuxR type systems in bacteria.;1 cl, 1 tbl, 1 ex, 1 dwg