METHOD FOR FUNCTIONAL CHARACTERISTICS OF PROTEINS FOR CLASSIFICATION OF PATIENTS TO BE ASSOCIATED TO A SPECIFIC DISEASE

摘要

The invention describes a method for functional characteristics of proteins for classification of patients to be associated to a specific disease performed in a computing device by applying biophysical parameters as an input to a marker linear combination, wherein the marker linear combination comprises a predefined combination of at least two biophysical parameters, using the marker linear combination to determine the input parameters relating to one or more of said predetermined diseases, and outputting a result according to the marker linear combination, wherein the marker linear combination comprises at least one of the biophysical parameters: a binding constant of a spin probe, a polarity surrounding a spin probe, an order parameter of a spin probe, a rotation correlation time of a spin probe, a spectral component from free spin probe molecules, a spectral component from spin probe on lipid-fraction of serum, or a geometry factor.