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Novel polypeptide selective binding with human programmed cell death protein 1 protein and uses thereof

机译:与人类编程细胞死亡蛋白1蛋白的新型多肽选择性结合和其用途

摘要

The present invention is a novel polypeptide capable of specifically binding to the programmed apoptosis protein 1, a polynucleotide encoding the polypeptide, a vector containing the polynucleotide, a recombinant microorganism into which the expression vector was introduced, and using the recombinant microorganism. It relates to a method for preventing or treating cancer, comprising administering a method for preparing the polypeptide, a composition for preventing or treating cancer comprising the polypeptide, and a composition for preventing or treating cancer comprising the polypeptide. Since the polypeptide of the present invention can bind to programmed apoptosis protein 1 and inhibit its activity, it can be widely used as a preparation for preventing or treating various diseases associated with programmed apoptosis protein 1.
机译:本发明是一种能够特异性结合编程的凋亡蛋白1的新型多肽,编码多肽的多核苷酸,含有多核苷酸的载体,引入了表达载体的重组微生物,并使用重组微生物。它涉及用于预防或治疗癌症的方法,包括施用用于制备多肽的方法,用于预防或处理包含多肽的癌症的组合物,以及用于预防或治疗包含多肽的癌症的组合物。由于本发明的多肽可以与编程的凋亡蛋白1结合并抑制其活性,因此可以广泛用作预防或治疗与编程的细胞凋亡蛋白1相关的各种疾病的制剂。

著录项

  • 公开/公告号KR20210023485A

    专利类型

  • 公开/公告日2021-03-04

    原文格式PDF

  • 申请/专利权人 한국과학기술원;

    申请/专利号KR1020190103737

  • 发明设计人 김학성;손수민;서효덕;박진호;

    申请日2019-08-23

  • 分类号C07K16/28;A61K39;A61P35;

  • 国家 KR

  • 入库时间 2022-08-24 17:31:54

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