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How to Inhibit Pathogenic Mutations Using a Programmable Base Editor System
How to Inhibit Pathogenic Mutations Using a Programmable Base Editor System
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机译:如何使用可编程基础编辑器系统抑制致病性突变
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摘要
Compositions and methods are provided herein that utilize a base editor comprising a polynucleotide programmable nucleotide binding domain and a nucleobase editing domain in association with a guide polynucleotide. Also provided herein is a base editor system for editing the nucleobase of a target nucleotide sequence.
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