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PARENTERAL PHARMACEUTICAL FORMULATION IN SUSPENSION, HAVING SUSTAINED RELEASE, IN LOW AND ULTRALOW DOSAGE, IN HORMONAL THERAPY IN THE CLIMACTERIC SYNDROME
PARENTERAL PHARMACEUTICAL FORMULATION IN SUSPENSION, HAVING SUSTAINED RELEASE, IN LOW AND ULTRALOW DOSAGE, IN HORMONAL THERAPY IN THE CLIMACTERIC SYNDROME
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机译:肠外药物制剂在悬浮液中,在血液治疗中持续释放,低和超低剂量,在血液疗法中的激素治疗中
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摘要
Parenteral pharmaceutical formulation or composition, in suspension, having sustained release, containing suspended particles of estradiol and progesterone for hormonal replacement in female mammals in low and ultralow dosage; the formulation consists of an injectable suspension comprising particles of estradiol, particles of progesterone, a surfactant agent, an isosmotic agent, a thickening agent, and one or more preservation agents, wherein the estradiol is in particles having a size between 1 and 100 microns and the progesterone is in particles having a size between 1 and 100 microns, for application thereof in parenteral, intramuscular, subcutaneous or intradermal pharmaceutical form.
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