ELECTRICAL CELL-SUBSTRATE IMPEDANCE MEASUREMENT SYSTEM WITH IMPROVED MEASUREMENT RANGE

摘要

In the present invention, in the electrical cell-substrate impedance measurement system, a well in which cells are in contact with a cell measurement region is formed on a substrate, and a reduced graphene oxide (rGO) and gold nanoparticles (AuNP) are formed in the well. ECIS (Electric Cell-Substrate Impedance Sensing) sensor is deposited to measure the impedance of the cell-substrate; Including a processor that receives the response signal generated from the ECIS sensor in analog form, but digitally analyzes the amplitude and phase characteristics for measuring the impedance of the cell from the response signal, it is effective for cell growth, and the measurement range is improved. It is characterized in that unit cost can be reduced.