Assessing a condition of a subject using non-contrast dual energy computed tomography

摘要

In some aspects, the present disclosure relates to a method for non-invasively assessing a myocardial region of a subject by computed tomography (CT). In one embodiment, the method comprises: acquiring non-contrast imaging data for a myocardial region of a subject using dual energy computed tomography (DECT) scanning; reconstructing, from the acquired non-contrast imaging data, monochromatic images for a plurality of energy levels in a range of energy levels; determining, based at least in part on the image reconstruction, attenuation values for each respective energy level of the plurality of energy levels; and performing at least one of detection and quantification of myocardial fibrosis based at least in part on differences in the attenuation values across the plurality of energy levels.