首页> 外国专利> method for the stabilization of aqueous solutions, vitamin a, d, e, k1 and / or carotenoiden and / or lipophilic derivatives of water-soluble vitamins contain.

method for the stabilization of aqueous solutions, vitamin a, d, e, k1 and / or carotenoiden and / or lipophilic derivatives of water-soluble vitamins contain.

机译:用于稳定水溶液的方法中,维生素a,d,e,k1和/或类胡萝卜素和/或水溶性维生素的亲脂性衍生物均含有。

摘要

Lipophilic compositions comprise a fat-soluble vitamin, a lipophilic derivative of a water-soluble vitamin, a carotenoid or any mixture of these, in admixture with a non-ionic emulsifier and an ionic wetting agent. The compositions may be mixed with water, or aqueous solutions of polyalcohols and/or hydrocolloids to give clear stable solutions. Vitamins may be A, D, E, K1, or lipophilic derivatives of water-soluble vitamins such as pantothenol cetyl ether, or pyridoxin tri-palmitate, or carotenoids. Preferred non-ionic emulsifiers are those containing polyoxyethylene groups; ionic wetting agents may be anionic, cationic, or amphateric, many being listed. Water-soluble vitamins, e.g. Vitamins C, B1, B2, B6, and nicotinamide, sugars, e.g. sucrose, sorbitol, glucose, invert sugar, and also starch syrup or glycerine are mentioned as the aforesaid polyalcohols, and hydrocolloids may be methyl cellulose, tragacanth, polyvinylpyrrolidone, polyvinyl alcohol, pectin, and/or guar gum. Examples are given for preparations containing many fat-soluble vitamin mixtures, which are then admixed with aqueous solutions which may contain water-soluble vitamins.
机译:亲脂性组合物包含脂溶性维生素,水溶性维生素的亲脂性衍生物,类胡萝卜素或它们的任何混合物,并与非离子乳化剂和离子润湿剂混合。可以将组合物与水或多元醇和/或水胶体的水溶液混合以得到透明的稳定溶液。维生素可以是A,D,E,K1或水溶性维生素的亲脂性衍生物,例如泛醇鲸蜡基醚,或吡啶甲酸三棕榈酸酯或类胡萝卜素。优选的非离子乳化剂是那些含有聚氧乙烯基的乳化剂。离子润湿剂可以是阴离子的,阳离子的或两性的,列出了许多。水溶性维生素,例如维生素C,B1,B2,B6和烟酰胺,糖,例如作为上述多元醇,提到了蔗糖,山梨糖醇,葡萄糖,转化糖以及淀粉糖浆或甘油,并且水胶体可以是甲基纤维素,黄aga胶,聚乙烯吡咯烷酮,聚乙烯醇,果胶和/或瓜尔胶。给出了包含许多脂溶性维生素混合物的制剂的实例,然后将其与可能包含水溶性维生素的水溶液混合。

著录项

  • 公开/公告号NL6412482A

    专利类型

  • 公开/公告日1965-05-03

    原文格式PDF

  • 申请/专利权人

    申请/专利号NL19640012482

  • 发明设计人

    申请日1964-10-27

  • 分类号A23K20/174;A23L33/15;A61K9/00;A61K9/107;B01F17/00;

  • 国家 NL

  • 入库时间 2022-08-23 16:06:40

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