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A methylamide synthesis procedure of 3fenil-3- (4-pyridyl) -3-hydroxypropionic and 3-phenyl-3- (2-piridyl) -3-hydroxypropionic acids. (Machine-translation by Google Translate, not legally binding)
A methylamide synthesis procedure of 3fenil-3- (4-pyridyl) -3-hydroxypropionic and 3-phenyl-3- (2-piridyl) -3-hydroxypropionic acids. (Machine-translation by Google Translate, not legally binding)
A process for the synthesis of methylamides of 3-phenyl-3- (4-pyridyl) -3-hydroxypropionic acid or 3-phenyl-3- (2-pyridyl) -3-hydroxypropionic acid characterized in that treats 4-benzoylpyridine and respectively 2-benzoylpyridine by ethyl chloroacetate in the presence of sodium ethylate and is then subjected to the action of anhydrous hydrochloric acid by proceeding to a catalytic dehalogenation of the product obtained by hydrogenating under ordinary conditions in the presence of of palladium on calcium carbonate and then treated by aqueous methylamine. (Machine-translation by Google Translate, not legally binding)
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