Procedure for the obtaining of basically replaced oximes. (Machine-translation by Google Translate, not legally binding)

摘要

Procedure for obtaining basically substituted oximes of general formula I ** (See formula) ** wherein A means a saturated or unsaturated chain of alkylene with 0-6 carbon atoms, B means an amino, alkylamino, dialkylamino, cycloalkylamino, dicycloalkylamino, cycloalkylalkylamino, dicycloalkylalkylamino, alkylarylamino, alkylarylkylamino, piperidino, pyrrolidino, hexamethyleneimino, morpholino radical , thiomorpholino, N-alkylpiperazine or N- (2-hydroxyalkyl) -piperazine, and n means 1 or 2 and X means -CH2-, - (CH2) 3 or -CH = CH- and R1 and R2 mean hydrogen, halogen-radicals alkyl with 1-4 carbon atoms, alkoxy radicals, alkylmercapto radicals with 1-4 carbon-hydroxy, nitro or amino or trifluoromethyl atoms, characterized in that ketones of general formula II are reacted ** (See formula) ** wherein R1 and R2 have the meaning indicated above or their ketals, chlorides or the corresponding thio-compounds with hydroxylamine and the oximes formed of general formula III ** (See formula) ** wherein R1 and R2 have the meaning indicated above in the form of their metal salts are partially reacted with dihalides of general formula IV Halogen-CH2 - A - Halogen (IV) wherein A has the above-indicated meaning and Halogen means a halogen atom, and the compounds formed of formula V ** (See formula) ** wherein R1, R2, A and Halogen have the meaning of before, they are then reacted with amines of general formula VI H-B (VI) where B has the meaning indicated above. (Machine-translation by Google Translate, not legally binding)