A method for the production of 17 - ketostatines - or 17 - hydroxy - 9ª, 10ª ≠ - steroids the androstane series by microbiological side-chain degradation of 20 - ketostatines - 9ª, 10ª ≠ - steroids the pregnane

摘要

1,136,072. Preparation of 10 α-methyl steroids. T. D. THREADGOLD (Philips' Gloeilampen Fabriken N.V.). 22 Dec., 1965 [25 Sept., 1964], No. 39168/64. Heading C2U. The invention comprises a process for producing a 17-keto or 17-hydroxy-9#, 10α- androstane by subjecting 20-keto-9#, 10α- pregnane not containing a 17α-hydroxy group to the action of Helicosporium fungi or spores or oxygenating enzyme systems thereof.