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A method for the production of acylasparaginaten and acyl - glutamates of the arginine

机译:一种生产精氨酸酰基乙酰氨基丁酸和酰基谷氨酸的方法。

摘要

The invention comprises arginine N-acyl-asparaginates and arginine N-acyl-glutamates and a process for their preparation comprising reacting arginine with an N-acyl-asparagine or an N-acyl-glutamine. N-Acyl-asparagines and N-acyl-glutamines are prepared by acylating asparagine or glutamine according to conventional methods. Pharmaceutical compositions, useful as cerebral and cardiac glutamics and aspartics, and as detoxifiers in hyperammoniaemia, comprise a compound of the invention and a pharmaceutical carrier.
机译:本发明包括精氨酸N-酰基天冬酰胺和精氨酸N-酰基谷氨酸,其制备方法包括使精氨酸与N-酰基天冬酰胺或N-酰基-谷氨酰胺反应。根据常规方法,通过将天冬酰胺或谷氨酰胺酰化来制备N-酰基天冬酰胺和N-酰基谷氨酰胺。可用作脑和心脏的谷氨酸和天冬氨酸以及高氨血症中的排毒剂的药物组合物包含本发明的化合物和药物载体。

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