首页> 外国专利> 6-alpha-3-acylthioureidophenylacetamido-and 6-alpha-3-acylthioureidoth - ie-nylacetamido-penicillanic acids antibacterial and feed additives

6-alpha-3-acylthioureidophenylacetamido-and 6-alpha-3-acylthioureidoth - ie-nylacetamido-penicillanic acids antibacterial and feed additives

机译:6-α-3-酰基硫脲基苯基乙酰胺基和6-α-3-酰基硫脲基苯基乙酰胺基-氨基乙酰氨基青霉酸抗菌和饲料添加剂

摘要

Cpds. of formula (I) (claimed) R1,R2,R3 = H, nitro, (lower)alkylamino, di(lower) alkylamino, (lower)alkanoylamino, amino, OH, (lower)alkanoyloxy, 1-6C alkyl, lower alkoxy, sulphamyl, Cl, I, Br, F or CF3 Z = lower alkyl, 4-7C cycloalkyl, monohalo(lower) alkyl, CHCl2, CCl3, 2-6C alkenyl, n = 0-3 integral R4,R5,R6 = H, NO2, di(lower)alkylamino, lower alkanoylamino, lower alkanoyloxy, 1-6C alkyl, lower alkoxy, sulphamyl, Cl, I, Br, F or CF3 X = H or non-toxic cation e.g. Na, K, Ca etc., NH4+, and substd. ammonium cations, e.g. cations of non-toxic amines such as triethylamine, procaine, dibenzylamine etc. (I) are antibacterial agents effective against gram negative and gram positive bacteria esp. Pseudomonas genus; nutritional supplements in animal feeds; therapeutic agents in poultry and animals.
机译:Cpds。式(I)的R 1,R 2,R 3 = H,硝基,(低级)烷基氨基,二(低级)烷基氨基,(低级)烷酰基氨基,氨基,OH,(低级)烷酰氧基,1-6C烷基,低级烷氧基,磺胺基,Cl,I,Br,F或CF3 Z =低级烷基,4-7C环烷基,单卤代(低级)烷基,CHCl2,CCl3、2-6C烯基,n = 0-3整数R4,R5,R6 = H ,NO2,二(低级)烷基氨基,低级烷酰基氨基,低级烷酰氧基,1-6C烷基,低级烷氧基,氨磺酰基,Cl,I,Br,F或CF3 X = H或无毒阳离子Na,K,Ca等,NH4 +和Substd。铵阳离子,例如无毒胺(如三乙胺,普鲁卡因,二苄基胺等)的阳离子。(I)是对革兰氏阴性和革兰氏阳性细菌尤其有效的抗菌剂。假单胞菌属;动物饲料中的营养补品;家禽和动物的治疗剂。

著录项

  • 公开/公告号FR2010848A1

    专利类型

  • 公开/公告日1970-02-20

    原文格式PDF

  • 申请/专利权人 BRISTOL MYERS CY;

    申请/专利号FR19690019856

  • 发明设计人

    申请日1969-06-13

  • 分类号A61K21/00;C07D99/00;

  • 国家 FR

  • 入库时间 2022-08-23 10:39:18

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