A process for the preparation of 9α, 21-difluoro-11β-hydroxy-16-methylene-17α-propionyloxypregna-1,4-diene-3,20-dione or the corresponding 11-oxo compound.

摘要

1,261,650. Antiinflammatory compositions. GLAXO LABORATORIES Ltd. 11 June, 1970 [12 June, 1969], No. 29866/69. Heading A5B. [Also in Division C2] Pharmaceutical compositions for anti-inflammatory use comprise 9, 21-fluoro-11#- hydroxy-16-methylene-17-propionyloxypregna - 1, 4-diene-3, 20-dione and/or the corresponding 11-one and suitable carriers. They may also contain antimicrobial agents, particularly antibiotics such as neomycin. Compositions for topical and internal use are described.