A procedure to produce derivatives of carboxylic acids fenoxialifaticos. (Machine-translation by Google Translate, not legally binding)

摘要

A process for producing phenoxyaliphatic carboxylic acid derivatives of the formula **(See formula)** wherein R1 and R2 are each unsubstituted or substituted hydrogen, C1-C8 alcohol, phenyl, naphthyl, benzyl, or phenethyl, or R1 and R2 may together with a carbon atom attached to them form a cycloalcohilidene group; R3 and R4 are each hydrogen or C1-C4 alcohol; Y is hydroxyl, C1-C4 phenoxy alkoxy or an amino radical of formula **(See formula)** where R5 and R6 are each hydrogen, C1-C4 alcohol, phenyl unsubstituted or substituted by halogen, alcohol or alkoxy, aralkoxy unsubstituted or substituted by halogen, alcohol or alkoxy, cycloalkoxy substituted or substituted by halogen, alcohol or alkoxy ; A represents hydrogen or a group of the formula **(See formula)** where R3, R4 and Y have the same meanings as defined above, and D and E are each a hydrogen atom a halogen atom, provided that R4 is C1-C4 alcohol when both R1 and R2 are methyl, which comprises (a) reacting a bisphenol derivative of the formula **(See formula)** where R1, R2, D and E are as defined, with a ketone compound of the formula **(See formula)** where R1, R2, R3, R4, D and E are as defined, and A'is a hydrogen atom or a group of the formula **(See formula)** where R3 and R4 are as defined, or (b) react a bisphenol derivative of formula **(See formula)** where R1, R2, D and E are as defined, with an aliphatic carboxylic acid derivative of the formula **(See formula)** where X is halogen or hydroxyl, and R3, R4 and Y are as defined to produce a phenoxyaliphatic carboxylic acid derivative of formula (I), or (c) to react a phenoxyaliphatic carboxylic acid derivative of formula **(See formula)** where R1, R2, R3, R4, A', D, and E are as defined above, with an esterification agent or an amine to produce aliphatic phenoxy carboxylic acid ester or amide of formula **(See formula)** where R1, R2, R3, R4, A', D, and E are as defined above, Y' is C1-C4 alkoxy, phenoxy, or an amine moiety of formula **(See formula)** where R5 and R6 are as defined in claim 1, A'' is hydrogen or a group of the formula **(See formula)** where R2, R4 and Y are as defined in claim 1. (Machine-translation by Google Translate, not legally binding)