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Androgenic and myotropic steroids - 3-keto-17-(bicyclo-(2,2,2)-octane -1'-methoxy carbonyloxy steroids

机译:雄激素和致肌性类固醇-3-keto-17-(双环-(2,2,2)-辛烷-1'-甲氧基羰氧基氧类固醇

摘要

Androgenic and myotropic 3-keto-17-(bicyclo 2,2,2 octane-1'-methoxy carbonyloxy) steroids Novel compounds of the formula: (where R1, R2, R3, R4 and R5 are H or CH3 and a, b and c = single or double bond. If R3 is H, b must be a single bond. If b is a single bond and R' is CH3 and the configuration of R1 is alpha. If one of the subst. R1, R2 and R4 is CH3 the others must be H. If R2 = CH3 b is a double bond) have androgenic and myotropic activity, are prepared either by reacting the 17-haloformate with the corresponding bicyclo 2,2,2 octane-1-methanol or by reacting the 17-alcohol with the corresponding bicyclo 2,2,2 octane-1-methyl haloformate.
机译:雄激素和同型3-酮17-(双环2,2,2辛烷-1'-甲氧基羰氧基)类固醇c =单键或双键;如果R3为H,则b必须为单键;如果b为单键且R'为CH3且R1的构型为alpha。如果R1,R2和R4之一是CH3,其他必须是H。如果R2 = CH3 b是一个双键)具有雄激素和肌同性活性,可通过使17-卤代甲酸酯与相应的双环2,2,2辛烷-1-甲醇反应或通过与17醇与相应的2,2,2辛烷-1-甲基卤代甲酸二环酯。

著录项

  • 公开/公告号DE000002023582A

    专利类型

  • 公开/公告日1971-11-25

    原文格式PDF

  • 申请/专利权人

    申请/专利号DE2023582A

  • 发明设计人

    申请日1970-05-14

  • 分类号

  • 国家 DE

  • 入库时间 2022-08-23 08:36:17

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