Amino-hydroxypropyl-coumarins - with coronary dilating activity

摘要

Coumarins of formula (I): (where R1 and R2 are H or is not 4C alkyl in which one H-atom can be replaced by an OH gp., at least one of R1 and R2 being other than H, or NR1R2 is a 5- or 6- membered heterocycle, and R3 is not 3C alkyl) and their salts with pharmacologically tolerable acids are strongly active coronary dilators which are more resistant to in vivo degradation than the known coronary dilator carbocromene.