Phenyl alkanoyl esters of 4-hydroxy-6-sulphonamido - quinolines - as analgesics antipyretics antiinflammatories antirheuma

摘要

Title cpds. are of formula (I): (where A is hydrocarbon gp.; R1 is H or 1 or 2 gps. selected from cycloalkyl, aryl, aralkyl and aralkenyl (opt. substd. by halogens, alkyl, CN, NO2, CF3, alkoxy or alkylthio), alkyl, alkenyl, halogens, CN, NO2, alkoxy, aryloxy, aralkoxy, alkylthio, arylthio, aralkylthio, aryloxymethyl, arylthiomethyl and CF3; R2 and R3 = alkyl(1-3C) or together form a heterocycle with the N atom which may contain a further N or O atom; R4 is H or CH3). The cpds. are prepd. by the reaction of the 4-OH quinoline with the phenylalkanoic acid halide.