Process of preparation of hydroxylated derivatives and carboxilados of terpenes from essential oils and especially pine and Eucalyptus tea

摘要

Essential oils, e.g. oil of pine, cajuput or eucalyptus are oxidized at not more than 80 DEG C. by the passage therethrough of a current of oxygen-rich gas, preferably in the presence of a catalyst, e.g. cobalt abietate, and the oxidation products (hydroxylated, carbonylated and carboxylated derivatives) are separated from unreacted oil may be fractional distillation; the unreacted oil may be recycled. The oxidation, for example with 90% air, 10% oxygen, is preferably carried out in a first phase at room temperature and in a second phase at 50-55 DEG C. with the catalyst introduced in separate portions during the first phase; the products will form well-defined hydrazones, and are claimed per se.ALSO:Pharmaceutical preparations with therapeutic activity towards respiratory ailments comprise an inert carrier and the oxidation product of pine, cajuput or eucalyptus essence. The said oxidation products are characterised by a yellow colour and the formation of a hydrazone, and are stated to by hydroxylated, carbonylated and carboxylated derivatives; they are derived from the essential oils by catalytic oxidation at under 80 DEG C., (see Division C5)