Procedure for the obtaining of amidas from amino acids. (Machine-translation by Google Translate, not legally binding)

摘要

Process for obtaining amides from amino acids, other compounds with acid and amino functions, characterized by adding an alkaline, alkaline-earth metal or bivalent or trivalent metal salt, in the form of halide, to the amino acid, carbonate, cyanide, etc., to form an amino acid metal chelate, by reacting the chelate, in an inert organic solvent, with a derivative of the type of 3,3-dimethyl-4-thio-6-amino acid 1-azobicyclo [3.2.0] heptane-2-carboxylic acid, to obtain an N-carboxyanhydride which, reacting with the amine functions of the aminated compounds, leads to the formation of the desired amide, eventually converting the obtained product into an alkali metal salt. (Machine-translation by Google Translate, not legally binding)