ANTIBIOTIC NEGAMYCIN FROM STREPTOMYCES PURPEOFUSCUS

摘要

Process for the production of an antibiotic substance called negamycin which comprises cultivating a strain of Streptomyces purpeofuscus A.T.C.C. 21470 in an aqueous carbohydrate solution containing a nitrogenous nutrient under aerobic conditions until substantial antibacterial activity is imparted to said solution and then recovering said negamycin from said solution and negamycin which is effective for inhibiting Pseudomonas, Salmonella, Shigella, Klebsiella, E.coli, Staphylococci and which has the following structure: