首页> 外国专利> Decapeptide l - the step of removing the embers amyl - lglutaminyl - l - aspartyl - l - tyrosyl - l - threonylglycyl - l - tryptophanyl- - l - methionyl - laspartyl - l - phenyl may be alanyl amide, and its salts and a method for the production thereof

Decapeptide l - the step of removing the embers amyl - lglutaminyl - l - aspartyl - l - tyrosyl - l - threonylglycyl - l - tryptophanyl- - l - methionyl - laspartyl - l - phenyl may be alanyl amide, and its salts and a method for the production thereof

机译:十肽l-去除余烬的步骤戊基-谷氨酰胺基-l-天冬氨酰-l-酪氨酰基-l-苏糖基甘氨酰基-l-色氨酸-l-甲硫酰基-laspartyl -l-苯基可以是丙氨酰胺及其盐和方法用于生产

摘要

preparation of the decapeptide L-pyroglytamyl-L-glumataminyl-L-aspartyl-L-tyrosyl-L-threonylglyc- yl-L-tryptofanyl-L-methionyl-L-aspartyl-L-phenylalanylamide in which the phenol group of the tyrosyl group is either free or blocked by a sulphur acid residue, and the alcohol group of the threonyl group is either free or blocked by an aliphatic acyl residue (1 to 4 C atoms), and the pharmaceutically acceptable salts of the above decapeptide with an organic or inorganic base. The peptide and its derivatives have the ability to stimulate the activity of the stomach-intestine canal as well as the secretion of the associated glands.
机译:制备十肽L-邻苯二甲酰基-L-谷氨酰胺基-L-天冬氨酰-L-酪氨酰基-L-苏氨酰甘氨酰-L-色氨酸基-L-甲硫酰基-L-天冬氨酰-L-苯丙氨酰胺,其中酪氨酰基的酚基巯基是游离的或被硫酸残基封闭的,苏氨酰基的醇基是游离的或被脂族酰基残基(1-4个碳原子)封闭的,并且上述十肽与有机或无机碱。该肽及其衍生物具有刺激胃肠道的活性以及相关腺体分泌的能力。

著录项

  • 公开/公告号DE000001643504C

    专利类型

  • 公开/公告日1973-09-06

    原文格式PDF

  • 申请/专利权人

    申请/专利号DE1643504A

  • 发明设计人

    申请日1967-08-04

  • 分类号C07C103/52;

  • 国家 DE

  • 入库时间 2022-08-23 07:12:05

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