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PROCESS FOR THE PRODUCTION OF A SACCHARASE INHIBITOR PROCESS FOR THE PRODUCTION OF A SACCHARASE INHIBITOR

机译:糖化酶抑制剂的生产过程糖化酶抑制剂的生产过程

摘要

The invention relates to a saccharase inhibitor derived from Actinoplanaceae Strain CBS 961.70, including mutants and variants thereof, means for the production of said saccharase inhibitors comprising cultivation of Actinoplanaceae Strain CBS 961.70, including mutants and variants thereof, in appropriate nutrient solutions which are characterized by being starch free under conditions most favorable to growth and production of said saccharase inhibitor and recovering a saccharase inhibitor from culture broths of said nutrient solutions, as well as the use of said inhibitor in pharmaceutically acceptable therapeutic compositions suitable for use in the treatment and relief of conditions indicative of adiposity, diabetes, pre-diabetes, hyperlipaemia (atherosclerosis), caries and the like.
机译:本发明涉及衍生自放线菌科CBS 961.70的糖酶抑制剂,包括其突变体和变体,生产所述糖酶抑制剂的方法,包括在合适的营养液中培养放线菌科CBS 961.70,包括其突变体和变体,其特征在于:在最有利于所述糖酶抑制剂的生长和生产并从所述营养液的培养液中回收糖酶抑制剂的条件下不含淀粉,以及所述抑制剂在适合用于治疗和缓解糖尿病的药学上可接受的治疗性组合物中的用途指示肥胖,糖尿病,糖尿病前期,高脂血症(动脉粥样硬化),龋齿等的疾病。

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