6-Pyridyl-3,6-dihydro-1,2-oxazines - with hypolipaemic, hypocholesterolae-mic and triglyceride-lowering props

摘要

Cpds. of formula (I) (where R1 is phenyl mono- or poly-substd. by is not 4C alkyl, CF3, is not 4C alkoxy or halogen; a 1,3,5(10)-oestratrien-3-yl residue opt. substd. in the 17beta-position by is not 4C alkoxy; or opt. functionally modified is not 10C carboxyalkyl) and their acid addn. salts, which have lipolysis-inhibiting, hypocholesterolaemic and triglyceride-lowering props. and are also useful as inters. for other pharmaceuticals, are pref. prepd. by reacting 1-(3-pyridyl)-1,3-butadiene with a nitroso cpd. R1NO.