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procedure for isolation of components in the aqueous losningar by adsorption of the aqueous losningarna on koncentreringshjelpmedel and efterfoljande extraction of components
procedure for isolation of components in the aqueous losningar by adsorption of the aqueous losningarna on koncentreringshjelpmedel and efterfoljande extraction of components
1467599 Chromatographic concentration MERCK PATENT GmbH 27 Feb 1975 [2 March 1974] 822875 Heading B1H [Also in Divisions Cl and G1] Components present in aqueous solution, for example drugs or drug metabolites in body fluids are isolated for analysis by adsorption of the components on a concentration agent comprising silica gel and/or Kieselguhr and subsequent extraction of the components with a lipophilic solvent, the concentration agent being a flowable silica gel and/or kieselguhr with an average particle size of 0.05 to 1.0 mm, and average pore volume of 0.2 to 3 ml/g and a specific surface of 0.2 to 50 mSP2/SP/g. The concentration agent may be used as a column packing in a glass or synthetic resin column length 5 to 20 cm, diameter 1 to 3 cm, the packing being retained by wadding or polypropylene mesh. The column may be a syringe barrel. Alternatively the packing may be in pillow- or sphere-shaped bags.
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机译:1467599色谱浓度MERCK PATENT GmbH 1975年2月27日[1974年3月2日] 822875标题B1H [也位于Cl和G1分部]分离水溶液中存在的组分,例如体液中的药物或药物代谢物,通过吸附在浓缩剂,其包含硅胶和/或硅藻土,随后用亲脂性溶剂萃取组分,该浓缩剂是可流动的硅胶和/或硅藻土,其平均粒径为0.05至1.0 mm,平均孔体积为0.2至3 ml / g,比表面积为0.2至50 m 2 SP> / g。浓缩剂可用作玻璃或合成树脂柱长5至20 cm,直径1至3 cm的柱填料,该填料可通过填料或聚丙烯网保留。该柱可以是注射器筒。或者,包装可以放在枕头或球形袋中。
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