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A method for the immunological detection of biological particles on a surface with the use of radioisotopes, as well as a device for carrying out the method

机译:一种利用放射性同位素对表面上的生物颗粒进行免疫学检测的方法,以及执行该方法的装置

摘要

ABSTRACT OF THE DISCLOSUREThe detection of immunologically reactive biologicalparticles such as viruses, bacteria and other cells is obtainedby detection of the occurrence of an immunological reaction ona substrate between the particle to be detected and itsradioactive-tagged antibody. A first immunologically reactivebiological particle is absorbed onto the surface of thesubstrate in a particular monomolecular layer pattern,and the substrate is then exposed to a solution suspectedof containing the particles to be detected which are specificto the first particle. Finally, the substrate is exposed tothe radioactive-tagged antibody to the particle to be detected,and the pattern substrate surface is monitored for radio-activity by searching for the particular pattern which emitsa high radiation level, if it exists.
机译:披露摘要免疫反应性生物学检测获得病毒,细菌和其他细胞等颗粒通过检测免疫反应的发生待检测粒子与其底物之间的底物放射性标记的抗体。第一免疫反应生物颗粒被吸收到具有特定单分子层图案的基材,然后将基材暴露于怀疑的溶液中包含要检测的特定粒子到第一个粒子。最后,将基材暴露于放射性标记的要检测颗粒的抗体,并监视图案基板表面是否有放射线通过搜索发出的特定模式进行活动高辐射水平(如果存在)。

著录项

  • 公开/公告号DE2461230A1

    专利类型

  • 公开/公告日1975-07-17

    原文格式PDF

  • 申请/专利权人 GEN ELECTRIC;

    申请/专利号DE19742461230

  • 发明设计人 GIAEVER IVAR;

    申请日1974-12-23

  • 分类号G01N33/16;

  • 国家 DE

  • 入库时间 2022-08-23 03:51:35

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